ONE MIND has numerous projects at various stages of development. The following are our flagship initiatives, which have been in development for over a year and are positioned for full operational launch in 2013.
GEMINI is a Public-Private Partnership combining best-in-class science, technology, and expertise. One Mind is catalyzing collaboration between international research Centers of Excellence, Industry, and government to accelerate the translation of basic science into breakthrough diagnostics and improved treatments for TBI & PTS.
TBI affects an estimated 10 million people worldwide and more than 1.7 million in the U.S. TBI is a silent epidemic--its complications are frequently invisible, thus difficult to diagnose and treat. TBI can lead to motor, cognitive, and social impairments that interfere with an individual’s ability to be productive.
PTS is a severe anxiety disorder that follows an event that causes psychological trauma. Early evidence suggests that as many as 20% of the approximately 1.64 million U.S. troops returning from deployments to Afghanistan and Iraq show symptoms of PTS or major depression. The psychological toll of multiple deployments--many involving prolonged exposure to combat-related stress--is high compared with physical injuries.
The GEMINI PROJECT TBI-PTS Knowledge Integration Network will accelerate advancements in diagnosis and treatment for veterans and civilians alike.
In 2013, One Mind will launch this multi-country, multi-site initiative to create a large-scale database of individuals with acute head trauma and/or psychological trauma with rigorous biomarker (e.g. genetics, imaging) and clinical measures to:
One Mind, in partnership with the International Neuroinformatics Coordinating Facility and other partners, is creating a digital environment for multiple-source data sharing, with open analysis tools, and provenance tracking systems for working with complex data. This system will foster an unprecedented open science approach among academia, industry, non-profits, and governments that will remove the barriers to effective scientific and clinical research and speed diagnosis and treatment.
A dynamic, on-line international registry of brain-related disorder biorepositories supported by the Neuroscience Information Framework (NIF), American Brain Coalition, and the NIH. Learn more at http://neuinfo.org/onemind
One Mind has joined the Orion Bionetworks Alliance for Multiple Sclerosis. Orion is a program of the Marin Community Fund, a non-profit 501(c)(3) corporation. Orion Bionetworks is a multidisciplinary computational modeling community that is harnessing the power of data, technology, and collaboration to pave the way for Systems Medicine and transform the research and treatment of multiple sclerosis and other brain disorders.
We are developing causal disease models with unprecedented predictive power that will drive progress towards better treatments and, ultimately, cures for multiple sclerosis and other devastating brain disorders.
To advance the understanding of brain disorders, Orion Bionetworks is building powerful, data-driven disease models.